Table 1.
Basic clinical characteristics among normal, OAMI, and PH-OAMI groups.
| Variables | Normal group (n = 56) | OAMI group (n = 52) | PH-OAMI group (n = 43) | P1 value | P2 value | P3 value | P4 value |
|---|---|---|---|---|---|---|---|
| Gender (male/female) | 41/15 | 41/11 | 33/10 | – | 0.510 | 0.810 | 0.816 |
| Age (years) | 63.30±10.17 | 65.73±10.60 | 70.12±13.41 | 0.003 | 0.232 | 0.082 | 0.005 |
| History | |||||||
| Hypertension (%) | 73.21 | 82.69 | 76.74 | – | 0.257 | 0.607 | 0.816 |
| Hyperlipidemia (%) | 7.14 | 7.69 | 9.30 | – | 1.000 | 1.000 | 0.725 |
| Diabetes (%) | 14.29 | 50.00 | 39.53 | – | 0.000 | 0.408 | 0.005 |
| Smoking (%) | 51.79 | 48.08 | 46.51 | – | 0.847 | 1.000 | 0.686 |
| Alcohol (%) | 17.86 | 21.15 | 16.28 | – | 0.808 | 0.607 | 1.000 |
| Heart function (grade) | 1.93±0.26 | 3.02±0.54 | 3.21±0.41 | 0.000 | 0.000 | 0.061 | 0.000 |
| Previous drug medication | |||||||
| Aspirin (%) | 26.78 | 82.69 | 88.37 | – | 0.000 | 0.565 | 0.000 |
| Clopidogrel/ticagrelor (%) | 0 | 51.92 | 46.51 | – | 0.000 | 0.682 | 0.000 |
| Statin (%) | 32.14 | 98.08 | 95.35 | – | 0.000 | 0.588 | 0.000 |
| ACEi/ARB (%) | 53.57 | 67.31 | 53.49 | – | 0.171 | 0.207 | 1.000 |
| Beta-blocker (%) | 37.50 | 63.46 | 65.12 | – | 0.012 | 1.000 | 0.008 |
| CCB (%) | 25.00 | 13.46 | 6.98 | – | 0.151 | 0.504 | 0.029 |
| Antidiabetes drug (%) | 7.14 | 26.92 | 34.88 | – | 0.009 | 0.503 | 0.001 |
| Furosemide/spironolactone (%) | 0 | 67.31 | 79.07 | – | 0.000 | 0.251 | 0.000 |
| Digoxin (%) | 0 | 15.38 | 13.95 | – | 0.002 | 1.000 | 0.005 |
OAMI: old anterior myocardial infarction; PH: pulmonary hypertension; ACEi: angiotensin-converting enzyme inhibitors; ARB, angiotensin II receptor blockers; CCB: calcium channel blocker.
Data were expressed as n (%), mean ± SEM. P1 value was shown a comparison among the three groups. P2 value was shown a comparison between normal and OAMI groups. P3 value was shown a comparison between OAMI and PH-OAMI groups. P4 value was shown a comparison between normal and PH-OAMI groups.