Table 2.
Laboratory and radiology findings at admission
| All patients (n = 319) |
Discharged (n = 238) |
Deceased (n = 81) |
p-value | |
|---|---|---|---|---|
| Laboratory findings | ||||
| White blood cell count (×10*9/L) | 6.33 (4.89–8.50) | 6.27 (4.80–8.41) | 6.63 (5.16–8.97) | 0.2258 |
| - > 10 | 45/315 (14.29) | 31/236 (13.14) | 14/79 (17.72) | 0.3505 |
| - < 4 | 37/315 (11.75) | 25/236 (10.59) | 12/79 (15.19) | 0.1795 |
| - Not measured | 4 | 2 | 2 | |
| Lymphocyte count (×10*9/L) | 0.75 (0.49–1.12) | 0.81 (0.53–1.21) | 0.63 (0.32–0.92) | 0.0720 |
| - < 1 | 211/314 (67.20) | 150/236 (63.56) | 61/78 (78.21) | 0.0097 |
| - Not measured | 5 | 2 | 3 | |
| Platelet count (×10*9/L) | 191 (157–254) | 196 (162–255) | 171 (126–243) | 0.0089 |
| - < 150 | 71/316 (22.47) | 42/237 (17.72) | 29/79 (36.71) | 0.0003 |
| - Not measured | 3 | 1 | 2 | |
| C-reactive protein (mg/L) | 76 (31–130) | 68 (28–110) | 96 (46–160) | 0.0120 |
| - Not measured | 7 | 4 | 3 | |
| Lactate dehydrogenase (U/L) | 320 (250–420) | 300 (230–400) | 390 (280–475) | < 0.0001 |
| - Not measured | 42 | 33 | 9 | |
| Ferritin (ug/L) | 840 (390–1600) | 735 (370–1500) | 1200 (490–2100) | 0.0073 |
| - Not measured | 90 | 62 | 28 | |
| D-dimer (mg/L) | 0.83 (0.53–1.41) | 0.78 (0.51–1.28) | 1.06 (0.62–1.67) | 0.3039 |
| - > 0.5 mg/L | 185/237 (78.06) | 133/177 (75.14) | 52/60 (86.67) | 0.1878 |
| - Not measured | 82 | 61 | 21 | |
| Aspartate aminotransferase (U/L) | 39 (28–56) | 39 (26–54) | 41 (31–60) | 0.4091 |
| - Not measured | 12 | 7 | 5 | |
| Alanine aminotransferase (U/L) | 28 (20–43) | 28 (20–43) | 28 (20–43) | 0.4939 |
| - Not measured | 13 | 8 | 5 | |
| Gamma-glutamyl transferase (U/L) | 45 (26–87) | 46 (25–86) | 42 (27–87) | 0.5703 |
| - Not measured | 22 | 14 | 8 | |
| Alkaline phosphatase (U/L) | 68 (57–93) | 67 (57–93) | 70 (58–90) | 0.4856 |
| - Not measured | 28 | 19 | 9 | |
| Total bilirubin (mg/dl) | 0.49 (0.38–0.68) | 0.49 (0.38–0.67) | 0.56 (0.38–0.72) | 0.9666 |
| - Not measured | 24 | 15 | 9 | |
| Creatinine (mg/dl) | 0.99 (0.79–1.31) | 0.94 (0.76–1.17) | 1.24 (0.92–2.21) | < 0.0001 |
| - Not measured | 9 | 7 | 2 | |
| eGFR (mL/min/1.73 m*2)b− | 70 (48–87) | 74 (58–91) | 48 (25–71) | < 0.0001 |
| - Not measured | 10 | 8 | 2 | |
| Sodium (mmol/L) | 137 (135–140) | 137 (134–139) | 138 (135–141) | 0.7515 |
| - Not measured | 7 | 5 | 2 | |
| Potassium (mmol/L) | 3.94 (3.60–4.26) | 3.91 (3.60–4.26) | 3.97 (3.58–4.26) | 0.4519 |
| - Not measured | 7 | 5 | 2 | |
| Arterial blood gas | ||||
| pH | 7.48 (7.45–7.51) | 7.48 (7.45–7.52) | 7.47 (7.43–7.48) | 0.0091 |
| - Not measured | 69 | 50 | 19 | |
| pO2 without suppl oxygen (mmHg) | 63 (55–71) | 64 (56–73) | 58 (50–67) | 0.0190 |
| - Hypoxemiaa — no. (%) | 212/241 (87.97) | 158/183 (86.34) | 54/58 (93.10) | 0.1105 |
| - Not measured | 78 | 55 | 23 | |
| pCO2 (mmHg) | 31 (28–34) | 31 (28–35) | 31 (28–34) | 0.8152 |
| - Not measured | 78 | 55 | 23 | |
| Lactate | 1.50 (1.10–1.90) | 1.40 (1.10–1.80) | 1.60 (1.30–2.30) | 0.0020 |
| - Not measured | 119 | 95 | 24 | |
| Radiology findings | ||||
| Infiltrates on chest X-ray | 205/292 (70.21) | 154/220 (70.00) | 51/72 (70.83) | 0.8931 |
| - Unilateral | 64/292 (21.92) | 49/220 (22.27) | 15/72 (20.83) | 0.7165 |
| - Bilateral | 140/292 (47.95) | 104/220 (47.27) | 36/72 (50.0) | 0.6846 |
aHypoxemia was defined as a PaO2 < 80 mmHg
bestimated glomerular filtration rate (eGFR) estimated using the CKD-EPI (Chronic Kidney Disease
Epidemiology Collaboration) equation