Table 1.
Summary Characteristics of Intervention Studies Examining T2D Remission.
| Study | Study design | Duration intensive | Duration total | Size | kcal | Controls | Weight loss (lbs) | Remission partial | Remission complete |
|---|---|---|---|---|---|---|---|---|---|
| Therapeutic studies | |||||||||
| Lean17,22 | Randomized | 4 months | 2 years | 298 | 839 | Standard | 19.4 | 42% | NR |
| Lim23 | Case control | 8 weeks | — | 24 | 1150 | Matched | 33.7 | 100% | 100% |
| Sarathi20 | Pre vs post | 3 months | 2 years | 32 | 1500 | NA | 16.3 | 46.9% | 46.9% |
| Steven24 | Pre vs post | 8 weeks | — | 30 | 662 | NA | 11.0 | 69% | NR |
| Umphonsathien21 | Pre vs post | 10 weeks | 14 weeks | 20 | 600 | NA | 21.0 | 75% | NR |
| Ranges | 8 weeks to 4 months | 8 weeks to 2 years | 20-298 | 600-1500 | 11-33.7 | 42% to 100% | 0% to 100% | ||
| Weighted means | 19.5 | 49.4% | |||||||
| Subtherapeutic studies | |||||||||
| Ades28 | Pre vs post | — | 6 months | 12 | −500 | NA | 21.3 | NR | 10% |
| Gow25 | Pre vs post | 8 weeks | 34 weeks | 8 | 800 | NA | 14.7 | 43% | NR |
| Gregg26 | Randomized | 1 year | 4 years | 5145 | 1500 | DSE | 7.7a | NR | 11% to 3.5% |
| McInnes27 | Randomized | 8-16 weeks | 20-28 weeks | 83 | −625 | Standard | 6.0 | 13% | NR |
| Ranges | 8 weeks to 1 year | 20 weeks to 4 years | 8-5145 | 800-1500 | 6-21.3 | 10% to 43% | 0% to 11% | ||
| Weighted means | 7.7 | 6.9% | |||||||
Abbreviations: NA, not applicable; NR, not reported.
a
Estimated (actual data not reported).