Table 1.
Clinical characteristics of subjects in the human autopsy pancreas cohort.
| Clinical Characteristics of Nondiabetic Subjects | ||||||||
|---|---|---|---|---|---|---|---|---|
| Case ID | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 |
| Age (y) | 84 | 65 | 86 | 60 | 81 | 61 | 80 | 64 |
| Sex (M/F) | M | M | M | M | M | M | F | F |
| BMI (kg/m 2 ) | 24.0 | 21.0 | 24.7 | 27.7 | 26.1 | 22.3 | 29.8 | 20.7 |
| Fasting glucose (mg/dL) | 89 | 95 | 77 | 88 | 117 | 90 | 97 | 106 |
| Time of death | 20:40 | 20:45 | 7:00 | 7:45 | 23:55 | 1:50 | 5:44 | 23:38 |
| Cause of death | Urothelial carcinoma | Acute myeloid leukemia | Sepsis | Ischemic heart disease | Acute bronchopneumonia | Biliary cirrhosis | Exsanguination | Fibrinous pneumonia |
| Clinical Characteristics of Type 2 Diabetic Subjects | ||||||||
| Case ID | 1 | 2 | 3 | 4 | 5 | 6 | 7 | |
| Age (y) | 62 | 75 | 90 | 84 | 64 | 67 | 80 | |
| Sex (M/F) | M | F | M | M | M | M | M | |
| BMI (kg/m 2 ) | 37.6 | 32.8 | 32.0 | 33.2 | 49.7 | 32.6 | 31.0 | |
| Fasting glucose (mg/dL) | 145 | 182 | 199 | 127 | 188 | 147 | 325 | |
| Time of death | 20:24 | 22:01 | 21:50 | 3:05 | 6:15 | 22:46 | 3:30 | |
| Diabetes medication | Metformin | Glyburide, metformin | Untreated | Insulin | Insulin | Insulin | Oral agents | |
| Cause of death | Pulmonary thromboembolism | Metastatic adenocarcinoma | Acute bronchopneumonia | Multisystem organ failure | Diabetic ketoacidosis | Atherosclerotic cardiovascular disease | Atherosclerotic disease | |