Table 3.
COX regression analysis for progression free survival (PFS).
| Factors | Univariate Analysis | Multivariate Analysis | |||
|---|---|---|---|---|---|
| HR (95% CI) | p Value | HR (95% CI) | p Value | ||
| Gender | male vs. female | 0.493 (0.169–1.435) | 0.194 | ||
| Age (year) | ≤58 vs. >58 | 0.943 (0.428–2.078) | 0.884 | ||
| Fuhrman Grade | G1+2 vs. G2+4 | 1.532 (0.660–3.588) | 0.321 | 1.259 (0.526–3.013) | 0.605 |
| Clinical Stage | I+II vs III + IV | 2.036 (0.926–4.475) | 0.077 | 0.823 (0.324–2.093) | 0.682 |
| Tumor Size | ≤4 cm vs. >4 cm | 2.562 (1.159–5.662) | 0.020 | 1.462 (0.608–3.512) | 0.396 |
| Tumor side | left vs. right | 0.634 (0.273–1.470) | 0.288 | ||
| Histologic Necrosis | Absent vs. present | 2.781 (1.259–6.142) | 0.011 | 2.858 (1.084–7.533) | 0.034 |
| PS status | PS- vs. PS+ | 12.957 (1.751–95.869) | 0.012 | 10.529 (1.362–81.419) | 0.024 |
| CPA | 0.938 (0.883–0.996) | 0.037 | 0.949 (0.889–1.013) | 0.116 | |
| PS | AggCPA | 0.928 (0.870–0.991) | 0.025 | ||
| DisCPA | 1.449 (0.948–2.213) | 0.087 | |||
| CPA | 1.025 (0.939–1.120) | 0.577 | |||
| Tumor | AggCPA | 1.027 (0.935–1.127) | 0.578 | ||
| DisCPA | 1.470 (0.411–5.258) | 0.554 | |||
HR: hazard ratio, PC: pseudo-capsule, CPA: collagen proportional area, DisCPA: percentage of distributed collagen proportional area, AggCPA: percentage of aggregated collagen proportional area.