Table 2.
Serum concentrations of EBV infection markers in patients with JIA, other types of arthritis, and controls. Results are presented as mean (median) ± standard deviation.
| EBV Infection Marker | JIA (n = 44) |
Other Types of Arthritis (n = 23) |
Control (n = 44) |
p-Value | |
|---|---|---|---|---|---|
| EA (U/mL) |
IgM | 0.69 (0.54) ± 0.38 |
0.66 (0.55) ± 0.32 |
0.68 (0.64) ± 0.34 |
0.90 |
| IgA | 0.33 (0.32) ± 0.14 |
0.42 (0.34) ± 0.23 |
0.34 (0.29) ± 0.20 |
0.23 | |
| IgG | 0.23 (0.19) ± 0.15 |
0.29 (0.17) ± 0.48 |
0.20 (0.14) ± 0.17 |
0.80 | |
| EBNA-1 (U/mL) |
IgA | 0.11 (0.1) ± 0.05 |
0.13 (0.11) ± 0.06 |
0.10 (0.07) ± 0.06 |
0.10 |
| IgG | 0.46 (0.51) ± 0.29 |
0.53 (0.66) ± 0.26 |
0.46 (0.44) ± 0.31 |
0.53 | |
| IgM | 0.19 (0.16) ± 0.08 |
0.23 (0.16) ± 0.18 |
0.20 (0.17) ± 0.13 |
0.87 | |
| VCA (U/mL) |
IgA | 0.23 (0.17) ± 0.22 |
0.26 (0.19) ± 0.20 |
0.24 (0.17) ± 0.21 |
0.40 |
| IgG | 0.96 (1.04) ± 0.51 |
0.67 (0.53) ± 0.57 |
0.91 (0.95) ± 0.54 |
0.11 | |
| Viral load | Copy number/µL | 0.34 (0) ± 0.74 |
2.14 (0) ± 5.92 |
0.48 (0) ± 0.81 |
0.65 |
| Copy number/µg DNA | 3.19 (0.00) ± 6.78 |
21.03 (0) ± 60.36 |
4.77 (0.00) ± 7.94 |
0.62 | |
| Copy number/100,000 cells | 2.10 (0.00) ± 4.48 |
13.88 (0.00) ± 39.84 |
3.15 (0.00) ± 5.24 |
0.62 | |
| DNA ng/µL | 101.13 (90.59) ± 32.90 |
102.8 (102.69) ± 35.35 |
94.98 (89.61) ± 29.23 |
0.76 | |
EA—early antigen; EBNA-1—Epstein-Barr nuclear antigen1; JIA—juvenile idiopathic arthritis; VCA—viral capsid antigen.