Figure 3.

(A) Adenocarcinoma of the ileo-caecal region in a Dex-treated Severe Combined Immunodeficiency (SCID) mouse after 62 days of C. parvum infection. Scale bar, 1000 μm. (B) Low-grade intraepithelial neoplasia in a murine colonic explant after 27 days of C. parvum infection characterized by reduction of the interglandular space (white arrow), and loss of nuclear polarity with slight pseudostratification (black arrow). Scale bar, 25  µm. (C) Cryptosporidium developmental stages were observed in apical position (arrows) within the epithelial cells in a human colon adenocarcinoma of a Lebanese patient. Scale bar, 5  µm. (Hematoxyline and Eosine). Photomicrographs (B,C) were slightly modified from [41] and [40], respectively.