Table 2.
IC50 (µg/mL) and selectivity index (SI) of Hibiscus schizopetalus by protocol C.
| Virus | Parameter | Sample | Standard | ||
|---|---|---|---|---|---|
| Et-E | DCM-F | Bu-F | Acyclovir | ||
| Adenovirus | IC50 | 58.89 b | 54.88 a | 108.31 d | 91.92 c |
| SI | 3.8 | 5.93 | 2.66 | 8.34 | |
| CoxB4 | IC50 | 72.0 b | 64.13 a | 107.30 c | 72.79 b |
| SI | 3.20 | 5.08 | 2.68 | 10.53 | |
| HSV I | IC50 | 66.86 d | 29.85 b | 50.94 c | 26.99 a |
| SI | 3.45 | 10.91 | 5.66 | 28.42 | |
| HSVII | IC50 | 126.65 c | 74.17 b | - | 68.60 a |
| SI | 1.82 | 4.39 | 11.18 | ||
| HAV | IC50 | - | 168.67 b | - | 95.40 a |
| SI | 1.93 | 8.04 | |||
The half maximal inhibitory concentration (IC50) was calculated in µg/mL; selectivity index (SI). Different superscripts (a, b, c & d) for a given value within a column indicate significant difference at p < 0.05 using Duncan’s Multiple Range test (DMRT). Ethanolic Extract (Et-E); Dichloromethane Fraction (DCM-F); n-Butanol Fraction (Bu-F). Coxsackie Virus (CoxB4); Herpes Simplex Virus Type I (HSV-I); Herpes Simplex Virus Type II (HSV-II); Hepatitis A Virus (HAV).