Table 1.
Survival analysis correlating PTGs and PNGs to NB aggressiveness.
| RNAseq498 | Affymetrix88 | |||||
|---|---|---|---|---|---|---|
| Covariate | HR | 95% CI | p Value | HR | 95% CI | p Value |
| MCM2 | 3.15 | (2.51–3.96) | <2 × 10−16 | 2.29 | (1.61–3.27) | 4.07 × 10−6 |
| FGF2 | 2.19 | (1.63–2.93) | 1.47 × 10−7 | 0.85 | (0.59–1.23) | 4.00 × 10−1 |
| CA9 | 1.85 | (1.37–2.49) | 4.57 × 10−5 | 2.28 | (1.24–4.2) | 7.00 × 10−3 |
| ADM | 1.6 | (1.38–1.97) | 3.06 × 10−8 | 1.36 | (0.89–2.06) | 1.40 × 10−1 |
| SERPINF1 | 1.44 | (1.24–1.68) | 2.56 × 10−6 | 1.49 | (1.13–1.97) | 4.00 × 10−3 |
| TINF2 | 1.4 | (0.75–2.59) | 2.80 × 10−1 | 1.58 | (0.53–4.74) | 4.00 × 10−1 |
| SNAI1 | 1.27 | (0.99–1.64) | 5.00 × 10−2 | 1.16 | (0.86–1.55) | 3.20 × 10−1 |
| BMI1 | 1.17 | (0.71–1.92) | 5.00 × 10−1 | 0.44 | (0.19–1.01) | 5.00 × 10−2 |
| ANGPT1 | 0.97 | (0.77–1.24) | 8.00 × 10−1 | 1.08 | (0.69–1.69) | 7.30 × 10−1 |
| DDIT3 | 0.78 | (0.53–1.15) | 2.00 × 10−1 | 0.77 | (0.45–1.33) | 3.50 × 10−1 |
| LIG4 | 0.74 | (0.53–1.05) | 9.00 × 10−2 | 0.73 | (0.43–1.22) | 2.40 × 10−1 |
| STMN1 | 0.69 | (0.51–0.94) | 1.00 × 10−2 | 0.82 | (0.46–1.45) | 5.00 × 10−1 |
| CCL2 | 0.68 | (0.59–0.78) | 1.82 × 10−7 | 1 | (0.77–1.31) | 9.40 × 10−1 |
| BIRC3 | 0.65 | (0.57–0.75) | 6.41 × 10−10 | 0.88 | (0.72–1.08) | 2.40 × 10−1 |
| TEK | 0.61 | (0.51–0.73) | 4.99 × 10−8 | 0.77 | (0.49–1.21) | 2.70 × 10−1 |
| SOX10 | 0.6 | (0.51–0.70) | 6.74 × 10−10 | 0.75 | (0.60–0.94) | 1.00 × 10−2 |
| OCLN | 0.56 | (0.46–0. 68) | 7.81 × 10−9 | 0.79 | (0.65–0.96) | 2.00 × 10−2 |
| ACSL4 | 0.52 | (0.37–0.73) | 1.70 × 10−4 | 0.44 | (0.23–0.82) | 1.00 × 10−2 |
| XIAP | 0.46 | (0.25–0.84) | 1.00 × 10−2 | 0.21 | (0.09–0.49) | 2.00 × 10−4 |
| ERCC5 | 0.23 | (0.13–0.38) | 1.88 × 10−8 | 0.36 | (0.13–0.95) | 4.00 × 10−2 |
Univariate analysis was assessed by Cox regression. Overall survival defined the time to event. Covariates are sorted by decreasing order of HR in the RNAseq498 dataset. HR = Hazard ratio. CI = Confidence interval.