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Schematic representation of the Fl-Q-ASO, EGFR mRNA and quadruplex-duplex hybrid containing a covalently attached ligand oBMVC-C3 (Fl-Q-ASO/EGFR) (A) and chemical structure of a oBMVC-C3 attached to 3′-end of Q-ASO-NH2 3′-amino-oligonucleotide (B).
