Table 3.
rDNA promoter SNVs (at positions +1 to +100) found in lung adenocarcinoma patients.
| Patient | Histology | Sex | Age | Stage | Germline | Somatic | Months Post-Surgery | Alive/Deceased |
|---|---|---|---|---|---|---|---|---|
| 1 | IMA | F | 67 | IA2 | −206 1, +49, +52 | 35.3 | Deceased | |
| 2 | Acinar | M | 78 | IIB | +49 | −72 1 | 44.5 | Deceased |
| 3 | Pleomorphic + Solid | M | 68 | IIA | +73 | 63.3 | Deceased | |
| 4 | Acinar | M | 63 | IB | +52 | 124.5 | Deceased | |
| 5 | Papillary | F | 74 | IIB | +52 | 84.1 | Deceased | |
| 6 | Acinar | M | 71 | IA2 | +52 | 80.5 | Deceased | |
| 7 | Acinar (ASQ) | M | 67 | IB | +52 | 24.8 | Deceased | |
| 8 | Papillary | M | 79 | IA | +52 | 22.9 | Deceased | |
| 9 | Papillary | F | 71 | IA3 | +52 | 28.1 | Deceased | |
| 10 | MIA | F | 67 | IA1 | +52 | 143.4 | Alive | |
| 11 | Papillary | M | 62 | IB | +52 | 123.1 | Alive | |
| 12 | Solid | M | 66 | IIB | +52 | 115.6 | Alive | |
| 13 | Papillary | F | 57 | IB | +52 | 145.9 | Alive | |
| 14 | Papillary | M | 79 | IVB | +52 | 50.7 | Alive |
rDNA, ribosomal RNA gene, ribosomal DNA; SNV, single-nucleotide variant; IMA, invasive mucinous adenocarcinoma; ASQ, adenosquamous carcinoma; MIA, minimally invasive adenocarcinoma; M, male; F, female; Stage, UICC TNM stage. 1 SNVs outside +1 to +100 were also detected in these cases.