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Cross comparison with historical control.
| Our study: n (%) | MPACT trial: n (%) | |
|---|---|---|
| Survival data | ||
| Progression-free survival, median (months) | 4.8 | 5.5 |
| Overall survival, median (months) | 9.1 | 8.5 |
| Grade 3 or 4 toxicities | ||
| Growth-factor support | 48 (66%) | 110 (26%) |
| Anemia | 7 (10%) | 53 (13%) |
| Neutropenia | 2 (2%) | 153 (38%) |
| Neutropenic fever | 0 (0%) | 14 (3%) |
| Thrombocytopenia | 3 (3%) | 52 (13%) |
| Neurotoxicity | 5 (5%) | 70 (17%) |
| Dose reduction in patients | ||
| Nab-paclitaxel | 3 (3%) | 41% |
| Gemcitabine | 7 (10%) | 47% |
