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. 2020 Nov 24;12:1758835920974212. doi: 10.1177/1758835920974212

Figure 3.

Figure 3.

High expression of PARPBP correlates with anthracycline resistance in breast cancer. (A) Representative images of immunohistochemical staining of PARPBP in chemo-resistant and non-resistant tumors are shown. Scale bars, 50 μm. (B) Expression of PARPBP in chemoresistant tumors were significantly higher than that in non-resistant breast tumors. (C) PARPBP/231 and Vector/231 cells were treated with various concentrations of EPI for 48 h. (D) PARPBP/BT549 and Vector/BT549 cells were treated with various concentrations of EPI for 48 h. *p < 0.05, **p < 0.01.

EPI, epirubicin; PARBP, PARP1 binding protein.