Fig. 1. E. coli clinical resistance models based on the ten most common ARGs in E. coli.

Proportion of resistant invasive E. coli clinical isolates to aminopenicillins a, fluoroquinolones b, third generation cephalosporins c, and aminoglycosides d against the relative abundance of the 10 most common ARGs in E. coli. The blue line shows the fitted clinical resistance from the beta regression model with resistance gene abundance as explanatory variable. Note that for some countries, data on clinical resistance was not available for all classes.