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. 2020 Nov 26;10:20616. doi: 10.1038/s41598-020-76785-w

Table 1.

Patient characteristics before and after implementation of CRRT quality improvement interventions.

Characteristics Total Before QI interventions After QI interventions p-valuea
Total patients, n (%) 1185 483 702 0.212
AKI 986 (83.2) 394 (81.6) 592 (84.3)
ESKD 199 (16.8) 89 (18.4) 110 (15.7)
Age (years), mean ± SD 56.6 ± 14.2 55.9 ± 13.9 57.1 ± 14.4 0.147
Sex, male, n (%) 712 (60.1) 290 (60.0) 422 (60.1) 0.980
Race, n (%) 0.254
White 1087 (91.7) 441 (91.3) 646 (92.0)
Black 91 (7.7) 41 (8.5) 50 (7.1)
Other 7 (0.6) 1 (0.2) 6 (0.9)
Weight (kg), median [IQR] 90.9 [75.0–109.9] 90.8 [71.0–110.0] 91.0 [77.0–109.1] 0.229
Hospital LOS (days), median [IQR] 14.6 [5.7–28.8] 14.0 [6.0–27.9] 15.1 [5.4–29.4] 0.544
ICU LOS (days), median [IQR] 8.9 [3.8–19.2] 8.6 [3.8–15.5] 9.6 [3.9–20.7] 0.072
Mechanical ventilation (days), median [IQR] 4.0 [1.0–8.0] 3.5 [1.0–7.3] 4.0 [1.0–8.0] 0.278
Total CRRT days, median [IQR] 3.1 [1.4–7.0] 3.0 [1.2–6.5] 3.3 [1.6–7.4] 0.086
SOFA score at ICU admission, median [IQR] 12.0 [9.0–14.0] 12.0 [10.0–15.0] 12.0 [9.0–14.0] 0.198
SOFA score at CRRT initiation, median [IQR] 14.0 [11.0–16.0] 13.0 [11.0–15.0] 14.0 [11.0–16.0] 0.476
CCI score, median [IQR] 4.0 [2.0–7.0] 5.0 [3.0–7.0] 4.0 [2.0–6.0] 0.030
Discharge disposition, n (%) 0.167
Alive 507 (42.8) 219 (45.3) 288 (41.0)
Dead 678 (57.2) 264 (54.7) 414 (59.0)

Before QI interventions period included data from September 2016 to December 2017 (total of 16 months before and during QI interventions). After QI interventions period included data from January 2018 to June 2019 (18 months).

AKI acute kidney injury, CCI Charlson comorbidity index, CRRT continuous renal replacement therapy, ESKD end-stage kidney disease, ICU intensive care unit, LOS length of stay, QI quality improvement, SOFA sequential organ failure assessment.

ap-value of comparison for data before and after QI interventions.