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. 2020 Nov 26;10:20616. doi: 10.1038/s41598-020-76785-w

Table 2.

Selected CRRT metrics before and after implementation of CRRT quality improvement interventions.

CRRT QI metrics Before QI interventions After QI interventions p-valuea
Jan–Jun 2018 Jul–Dec 2018 Jan–Jun 2019
CRRT modality (CVVHDF), % 92.4% 95.1% 96.6% 100.0% < 0.001
Anticoagulation (RCA), % No data 23.1% 24.7% 39.5% < 0.001
Total RCA/RCA-CRRT hours, mean ± SD No data 0.62 ± 0.30 0.68 ± 0.27 0.73 ± 0.26 0.004
Delivered effluent dose (ml/kg/h), mean ± SD 30.50 ± 4.18 27.67 ± 2.07 28.17 ± 1.83 30.33 ± 3.14 0.939
Delivered/prescribed effluent dose, mean ± SD 0.88 ± 0.07 0.88 ± 0.02 0.88 ± 0.01 0.90 ± 0.02 0.487
Filter life span (hours), mean ± SD 26.00 ± 3.16 30.17 ± 4.96 31.00 ± 2.83 31.17 ± 3.31 0.020
Filters per patient, mean ± SD 3.56 ± 0.78 2.90 ± 0.87 2.75 ± 0.50 2.67 ± 0.64 0.054
CRRT access alarms per treatment day, mean ± SD 2.95 ± 1.02 2.02 ± 0.64 1.63 ± 0.20 1.68 ± 0.50 0.021
Total filter cost per 100-patient (USD) ± SD 80,010 ± 17,519 65,173 ± 19,614 61,744 ± 11,287 59,876 ± 14,292 0.054

The period before QI interventions included data from September 2016 to February 2017 (6 months).

CRRT continuous renal replacement therapy, CVVHDF continuous veno-venous hemodiafiltration, RCA regional citrate anticoagulation, USD United States dollars.

ap-value of comparison for data before QI interventions and from the last 6 months after QI interventions (Jan 2019–Jun 2019). If data before QI interventions were not available, data from the first 6 months after QI interventions (Jan 2018–Jun 2018) were used as reference.