Alterations in the body weight change of the animals throughout our experiment. Body weight change is represented by % between the first and third days of the TNBS procedure. Abs. control (no treatment), 50% EtOH (50% ethanol enema), TNBS (2,4,6-trinitrobenzenesulfonic acid enema), FLV (TNBS enema + 1 mg/kg fluvoxamine (FLV)), BD1063 (TNBS enema + 0.1 mg/kg BD1063), FLV + BD1063 (TNBS enema + 1 mg/kg FLV + 0.1 mg/kg BD1063), Saline (TNBS enema + 0.9% physiological saline), DMSO (TNBS enema + 3% dimethyl sulfoxide). Data representation: mean ± SEM; n = 5–12/group; * p < 0.01 TNBS vs. TNBS + treatment; # p < 0.05 absolute control vs. TNBS.