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. 2020 Nov 4;9(11):1081. doi: 10.3390/antiox9111081

Figure 4.

Figure 4

Effects of the activation and antagonism of sigma-1 receptor on the levels of GSH in TNBS-induced colitis. Abs. control (no treatment), 50% EtOH (50% ethanol enema), TNBS (2,4,6-trinitrobenzenesulfonic acid enema), FLV (TNBS enema + 1 mg/kg fluvoxamine (FLV)), BD1063 (TNBS enema + 0.1 mg/kg BD1063), FLV + BD1063 (TNBS enema + 1 mg/kg FLV + 0.1 mg/kg BD1063). Data representation: mean ± SEM; n = 5–10/group; * p < 0.05 TNBS vs. TNBS + treatment; # p < 0.05 absolute control vs. TNBS; & p < 0.05 EtOH vs. TNBS; a p < 0.05 Abs. control vs. EtOH.