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Changes in the activity of the antioxidant superoxide dismutase (SOD) enzyme through the administration of the sigma-1 receptor agonist and antagonist. Abs. control (no treatment), 50% EtOH (50% ethanol enema), TNBS (2,4,6-trinitrobenzenesulfonic acid enema), FLV (TNBS enema + 1 mg/kg fluvoxamine (FLV)), BD1063 (TNBS enema + 0.1 mg/kg BD1063), FLV + BD1063 (TNBS enema + 1 mg/kg FLV + 0.1 mg/kg BD1063). Data representation: mean ± SEM; n = 5–11/group.
