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Sural nerve biopsy from a 69-year-old Tyr78Phe patient (a): semithin section stained with toluidine blue. A moderate fiber loss is observed. Many fibers are surrounded by thin myelin sheath. Several regenerating clusters are present. Teased fibers examination from a 44-year-old patient with Glu89Gln (b) and from a 73-year-old patient with Phe64Leu (c). A segmental demyelination is present in b while a paranodal demyelination is noted in c.
