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Sural nerve biopsy from a 76-year-old Val30Met hATTR patient. Semithin section stained with Toluidine blue (a) showed amyloid deposition confirmed also by H&E (b) and Congo red (c) staining. However, immunofluorescence with anti-TTR (d), anti-kappa light chain (e), and anti-lambda light chain (f) resulted not specific for TTR amyloidosis. No MGUS was detected in this patient.
