Table 3.
Prevalence of non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) in patients with resected intrahepatic cholangiocarcinoma (iCCA) without classical risk factors and liver donors.
| Group | iCCA Patients | Liver Donors | p | Risk Ratio (95% CI) | E-Value (95% CI Closest to the Null) |
|---|---|---|---|---|---|
| All patients (F0–F4) | |||||
| NAFLD | 59/129 (45.7) | 50/129 (38.8) | 0.313 | 1.18 (0.89–1.57) | 1.64 (1.00) |
| NASH | 29/129 (22.5) | 8/129 (6.2) | <0.001 | 3.63 (1.72–7.63) | 6.71 (2.84) |
| No significant fibrosis (F0–F2) | |||||
| NAFLD | 53/115 (46.1) | 49/115 (42.6) | 0.690 | 1.08 (0.80–1.46) | 1.38 (1.00) |
| NASH | 21/115 (18.2) | 5/115(4.3) | 0.001 | 4.20 (1.64–10.76) | 7.87 (2.66) |