Table 4.

Comparison of CancerGram and AntiCP 2.0 [13] performance on the independent data set. AntiCP 2.0 predictions were obtained using model 1 of the standalone version with default values of threshold (0.5) and window length (10). CancerGram predictions were binarized. The low values of the Matthews correlation coefficient (MCC), precision and sensitivity are due to the large number of AMPs (769) and low number of ACPs (57) in the independent data set.

Software	MCC	Precision	Sensitivity	Specificity	Accuracy	AUC
CancerGram	0.15	0.17	0.30	0.89	0.85	0.60
AntiCP 2.0	0.07	0.10	0.32	0.79	0.76	0.53