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Casp double-knockout (DKO) mice reduced hepatocellular function as measured by serum alanine aminotransferase (ALT). WT and Casp DKO mice had a significant increase in ALT levels following IR. Decreased levels of ALT were observed in Casp DKO mice compared to WT mice. Means and standard deviations are shown. n = 6 per group. * p < 0.05.
