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. 2020 Nov 26;10(11):e038471. doi: 10.1136/bmjopen-2020-038471

Table 2.

Mixed model investigating the relationship between categories of TYA care received during the first 12 months from diagnosis and total quality of life and domain scores over 3 years (n=733)

Difference in means 95% CI P value†
Total quality of life score (n=733)
 TYA care category (v NO-TYA-PTC) SOME-TYA-PTC −5.63 −8.49 to −2.77 p=0.0005
ALL-TYA-PTC −4.17 −7.28 to −1.07
Physical functioning (n=733)
 TYA care category (v NO-TYA-PTC) SOME-TYA-PTC −8.28 −11.95 to −4.61 p=0.0001
ALL-TYA-PTC −4.79 −8.76 to −0.81
Emotional functioning (n=733)
 TYA care category (v NO-TYA-PTC) SOME-TYA-PTC −4.29 −7.79 to −0.80 p=0.015
ALL-TYA-PTC −5.43 −9.29 to −1.57
Social functioning (n=733)
 TYA care category (v NO-TYA-PTC) SOME-TYA-PTC −2.96 −5.77 to −0.16 p=0.099
ALL-TYA-PTC −2.49 −5.60 to 0.62
Work/school/college functioning (n=595)
 TYA care category (v NO-TYA-PTC) SOME-TYA-PTC −6.87 −10.45 to −3.30 p=0.0007
ALL-TYA-PTC −4.67 −8.47 to −0.87
Psychosocial summary score (n=600)
 TYA care category (v NO-TYA-PTC) SOME-TYA-PTC −2.51 −5.71 to 0.70 p=0.074
ALL-TYA-PTC −3.96 −7.44 to −0.48

*Results from a three category of care model for repeated measurements of quality of life over time since diagnosis, with a random effect for geography and adjustment for time since diagnosis, age at diagnosis, type of cancer, socioeconomic status, severity of cancer, ethnicity, choice about where to receive treatment, long-term condition prior to cancer, days from first symptom to diagnosis, number of general practitioner visits before diagnosis. Missing data for 96 due to missing TYA category and missing data in other covariates.

†Likelihood ratio test.

TYA, teenagers and young adults; TYA-PTC, TYA principal treatment centres.