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. 2020 Nov 26;10(11):e044126. doi: 10.1136/bmjopen-2020-044126

Table 3.

Sex-specific risk factors of 1-year mortality in the historical cohort (1994–1998)

Variable Women Men Multiplicative interaction
HR (95% CI) HR (95% CI) P value*
Age category
 40–64 years Reference Reference 0.004
 65–74 years 1.45 (1.32 to 1.59) 1.63 (1.51 to 1.75)
 75–84 years 2.06 (1.89 to 2.24) 2.42 (2.25 to 2.60)
 >85 years 3.53 (3.24 to 3.85) 3.70 (3.41 to 4.00)
Benign hypertension 0.70 (0.67 to 0.73) 0.82 (0.79 to 0.86) <0.001
Myocardial infarction 1.26 (1.16 to 1.36) 1.02 (0.95 to 1.10) <0.001
COPD/asthma 1.10 (1.05 to 1.16) 1.20 (1.15 to 1.25) 0.01
Renal disease 2.26 (2.04 to 2.50) 1.90 (1.74 to 2.07) 0.01
Diabetes 1.31 (1.25 to 1.38) 1.20 (1.14 to 1.26) 0.01

*Multiplicative interaction terms were formed by multiplying sex by each of the covariates in the multivariable Cox proportional hazard model for 1-year mortality. Only significant interaction terms (ie, ones demonstrating sex-specific risk factors) were reported in this table.

COPD, chronic obstructive pulmonary disease.