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. 2020 Oct 28;12(11):2506. doi: 10.3390/polym12112506

Figure 1.

Figure 1

Multicellular tumor spheroids (MCTS) biology. MCTS provide an in vitro platform for the investigation of cell–cell and cell–extracellular matrix (ECM) interactions. Additionally, MCTS mimic in vivo solid tumors in terms of nutrient, oxygen and pH gradients and zone formation.