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. 2020 Sep 4;40(6):738–751. doi: 10.1111/opo.12731

Table 7.

Summary of previously reported ARAM prevalence compared to the present study

n Summary
Graf et al. 1993
Control Subjects 15

  • ARAM was not found in healthy controls

  • ARAM was found in 14.3% of POAG patients with nonprogressive visual field loss in 5 years

  • ARAM was found in 86.7% of POAG patients with progressive visual field loss

  • ARAM was found in 68.8% of NTG patients

  • Prevalence of ARAM may not be the same in all glaucomas
Eyes x
Glaucoma Subjects 45
Eyes x
Grieshaber et al. 2007
Control Subjects 0

  • ARAM was found in 32.8% of POAG eyes

  • More female patients (40.9%) had ARAM compared to male patients (18.4%)

  • ARAM was strongly related to peripheral vascular dysregulation

  • ARAM was moderately related to stage of POAG quantified by Doctor

  • ARAM was not related to age or eye‐side
Eyes 0
Glaucoma Subjects 93
Eyes 186
Grieshaber et al. 2012
Control Subjects 35

  • ARAM was not found in age‐matched healthy controls

  • ARAM was found in 84.21% to 94.79% of POAG eyes

  • ARAM may compensate or mask RNFL loss

  • Time‐domain OCT is unable to visualize and differentiate ARAM from RNFL
Eyes 58
Glaucoma Subjects 19
Eyes 32
Nutzi et al. 2017
Control Subjects 0

  • Targeted specifically POAG patients with ARAM

  • The proportion of ARAM per eye correlated inversely with retinal sensitivity and corresponding RNFL sector thickness

  • Higher density of ARAM in an eye may be a clinical and structural sign for more advanced glaucoma
Eyes 0
Glaucoma Subjects 12
Eyes 18
Ashimatey et al. 2018
Control (younger) Subjects 35

  • ARAM was found in 55% of older controls but not in younger controls, showing an age effect

  • ARAM was found in 73% of patients with glaucoma

  • Patients with glaucoma tend to have larger retinal areas with ARAM

  • Extent of ARAM and its distribution was not predictive of retinal hemifield with the most damage
Eyes 35
Control (older) Subjects 42
Eyes 42
Glaucoma Subjects 38
Eyes 38
Cheung et al. 2020
Control Subjects 805

  • ARAM was found in 15% to 16% of healthy controls

  • ARAM was found in 15% to 23% of patients

  • ARAM was found in 17% to 19% of age‐similar sex‐matched healthy controls

  • ARAM was found to be related to age as well as posterior vitreous detachment

  • ARAM was not found to be related to sex
Eyes 1337
Glaucoma Subjects 146
Eyes 250