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. 2020 Sep 17;26(60):13578–13583. doi: 10.1002/chem.202002241

Scheme 2.

Scheme 2

Synthesis of functionalised cytochalasins. Reagents and conditions: a) dioxane, H2O, tris(2‐carboxyethyl)phosphine (TCEP), RT, 1 h; b) N,N‐diisopropylethylamine (DIPEA), DMF, CuI (0.05 equiv), RT, 12 h.