TABLE 1.
Demographics and baseline characteristics of the patients
| Tel/Aml 80/5 mg + Ros 20 mg (N = 66) | Tel/Aml 80/5 mg (N = 66) | Tel 80 mg + Ros 20 mg (N = 65) | Total (N = 197) | |
|---|---|---|---|---|
| Age (years) | 68.33 ± 8.31 | 66.09 ± 10.43 | 64.89 ± 9.11 | 66.45 ± 9.39 |
| Sex, Male, n (%) | 45 (68.18) | 48 (72.73) | 46 (70.77) | 139 (70.56) |
| Height (cm) | 163.56 ± 8.65 | 164.27 ± 9.21 | 163.10 ± 8.11 | 163.65 ± 8.64 |
| Weight (kg) | 70.56 ± 12.58 | 72.13 ± 10.78 | 70.97 ± 11.56 | 71.22 ± 11.62 |
| BMI (kg/m2)CHD risk factors, n (%) | 26.26 ± 3.40 | 26.67 ± 2.81 | 26.60 ± 3.23 | 26.51 ± 3.14 |
| Current Smoker | 10 (15.15) | 15 (22.73) | 11 (16.92) | 36 (18.27) |
| DBP ≥90 mm Hg | 24 (36.36) | 33 (50.00) | 37 (56.92) | 94 (47.72) |
| HDL‐C <40 mg/dL | 16 (24.24) | 16 (24.24) | 12 (18.46) | 44 (22.34) |
| Family history of premature CHD | 6 (9.09) | 2 (3.03) | 2 (3.08) | 10 (5.08) |
| (−) HDL‐C ≥60 mg/dL | 11 (16.67) | 16 (24.24) | 12 (18.46) | 39 (19.80) |
| Diabetes mellitus* | 28 (42.42) | 29 (43.94) | 32 (49.23) | 89 (45.18) |
| Coronary and peripheral arterial disease | 40 (60.61) | 38 (57.58) | 39 (60.00) | 117 (59.39) |
| 10‐y risk >20% | 31 (46.97) | 30 (45.45) | 21 (32.31) | 82 (41.62) |
| Cardiovascular risk category | ||||
| Group 1 (risk factor 0‐1) | 1 (1.52) | 2 (3.03) | 2 (3.08) | 5 (2.54) |
| Group 2 (risk factor ≥2 and 10‐y risk ≤20%) | 6 (9.09) | 6 (9.09) | 5 (7.69) | 17 (8.63) |
| Group 3 (CHD or CHD equivalence or 10‐y risk >20%) | 59 (89.39) | 58 (87.88) | 58 (89.23) | 175 (88.83) |
| Chronic kidney disease, n (%) | 3 (4.55) | 5 (7.58) | 1 (1.54) | 9 (4.57) |
| Baseline values | ||||
| MSSBP (mm Hg) | 155.40 ± 12.12 | 155.00 ± 12.09 | 154.42 ± 12.86 | 154.94 ± 12.30 |
| MSDBP (mm Hg) | 87.60 ± 8.61 | 89.49 ± 9.99 | 88.54 ± 11.17 | 88.54 ± 9.95 |
| LDL‐C (mg/dL) | 160.12 ± 32.34 | 153.41 ± 31.30 | 153.88 ± 36.73 | 155.81 ± 33.49 |
| Total cholesterol (mg/dL) | 225.55 ± 34.29 | 218.17 ± 36.91 | 221.20 ± 38.74 | 221.64 ± 36.62 |
| Triglyceride (mg/dL) | 170.68 ± 78.79 | 159.27 ± 67.87 | 174.26 ± 84.14 | 168.04 ± 77.06 |
| HDL‐C (mg/dL) | 46.38 ± 10.89 | 47.80 ± 12.04 | 47.89 ± 12.88 | 47.36 ± 11.92 |
| LDL‐C/HDL‐C | 3.59 ± 0.94 | 3.38 ± 0.98 | 3.42 ± 1.16 | 3.46 ± 1.03 |
| TC/HDL‐C | 5.05 ± 1.08 | 4.79 ± 1.19 | 4.89 ± 1.41 | 4.91 ± 1.23 |
Data are mean ± SD or n (%).Percentage denominator is the number of patients in each column.
Abbreviations: Aml, Amlodipine; BMI, Body Mass Index; CHD, Coronary Heart Disease; DBP, Diastolic Blood Pressure; HDL‐C, High Density Lipoprotein Cholesterol; LDL‐C, Low‐Density Lipoprotein Cholesterol; MSDBP, Mean Sitting Diastolic Blood Pressure; MSSBP, Mean Sitting Systolic Blood Pressure; Ros, Rosuvastatin; TC, Total Cholesterol; Tel, Telmisartan.
*
Patients with FPG (fasting plasma glucose) ≥ 126 mg/dL or HbA1c ≥6.5% at screening.