Table 3.
The effect of interactions between CARD8, NLRP3, IL1B, and IL6 polymorphisms on PCOS risk.
| Interaction | OR (95% CI) | p |
|---|---|---|
| CARD8 rs2043211 and IL1B rs1143623 | 1.27 (0.43–3.80) | 0.666 |
| CARD8 rs2043211 and IL1B rs16944 | 0.67 (0.22–2.06) | 0.480 |
| CARD8 rs2043211 and IL6 rs1800795 | 0.26 (0.09–0.81) | 0.020 |
| NLRP3 rs35829419 and IL1B rs1143623 | 0.71 (0.31–1.62) | 0.412 |
| NLRP3 rs35829419 and IL1B rs16944 | 1.21 (0.18–8.28) | 0.843 |
| NLRP3 rs35829419 and IL6 rs1800795 | 1.41 (0.23–8.58) | 0.707 |
| IL1B rs1143623 and IL6 rs1800795 | 3.17 (1.04–9.65) | 0.042 |
| IL1B rs16944 and IL6 rs1800795 | 0.44 (0.14–1.37) | 0.158 |
statistically significant p-values are bolded.