Figure 6.

Protein expression profile of cell cycle regulating proteins: Pixel density analysis (Western blot) of the cell cycle regulating proteins p21 (a), p27 (b), cyclin A (c), cyclin B (d), CDK1 (e), pCDK1 (f), and CDK2 (g) in parental and resistant Caki-1 cells after 48 h exposure to ART (20 µM), compared to untreated controls (set to 100%). Each protein analysis was accompanied and normalized by a housekeeping protein. Error bars indicate standard deviation (SD). Significant difference to untreated control: * p ≤ 0.05, ** p ≤ 0.01, *** p ≤ 0.001, ns = not significant. n = 4. For detailed information regarding the Western blots see Figure S1a–g.