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. 2020 Oct 27;9(11):3448. doi: 10.3390/jcm9113448

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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18F-NaF uptake in specific damaged skin/arteries in PXE. Damaged skin in neck (arrows (1A,1B)) and axillary folds (arrows (2A,2B)) vs healthy skin in lumbar region (3A,3B) on PET/CT imaging. Molecular calcification targeted with 18F-NaF. Damaged femoral arteries on PET/CT imaging. Molecular calcification targeted via PET/CT demonstrating 18F-NaF femoral arteries wall uptake (arrows (4A,4B)). 18F-NaF uptake absent in popliteal arteries walls (5A,5B). Maximum intensity projection indicates damaged vascular and skin sites (arrow 6).