Table 2.
Assessment of LGCI using 18F-FDG-PET-CT and ectopic calcification using 18F-NaF-PET-CT.
| All PXE Patients (n = 23) | ||||||||
| 18F-FDG PET-CT | 18F-NaF PET-CT | |||||||
| SKIN | SUV max | p | SUV max | p | ||||
| Lumbar (Reference Region) (median (IQR)) | 0.90 (0.80;1.10) | 0.70 (0.50;0.90) | ||||||
| Neck (median (IQR)) | 1.30 (1.20;1.90) | <0.0001 | 4.50 (3.20;5.10) | <0.0001 | ||||
| Axillary Folds (median (IQR)) | 1.80 (1.60;1.90) | <0.0001 | 2.75 (1.90;3.30) | <0.0001 | ||||
| All PXE Patients (n = 23) | PXE Patients with CS = 0HU (n = 11) | |||||||
| 18F-FDG PET-CT | 18F-NaF PET-CT | 18F-FDG PET-CT | 18F-NaF PET-CT | |||||
| ARTERIES | TBR max | p | TBR max | p | TBR max | p | TBR max | p |
| Popliteal (Reference Region) (median (IQR)) | 0.91 (0.80;1.14) | 1.12 (0.99;1.30) | 1.06 (0.73;1.14) | 1.00 (0.85;1.15) | ||||
| Carotid (median (IQR)) | 1.04 (0.88;1.18) | 0.93 | 1.25 (0.93;1.75) | 0.16 | 0.88 (0.74;1.08) | 0.32 | 1.14 (0.93;1.92) | 0.01 |
| Aorta (Ascending and Arch) (median (IQR)) | 1.32 (1.13;1.57) | <0.0001 | 1.42 (1.25;1.63) | 0.0004 | 1.24 (1.05;1.43) | 0.03 | 1.29 (1.06;1.64) | <0.01 |
| Aorta (Descending and Adominal) (median (IQR)) | 1.02 (0.88;1.36) | 0.09 | 0.78 (0.70;1.04) | 0.07 | 0.95 (0.88;1.29) | 0.24 | 0.78 (0.70;0.90) | 0.19 |
| Iliac (median (IQR)) | 0.93 (0.74;1.15) | 0.29 | 0.90 (0.75;1.32) | 0.48 | 0.93 (0.63;1.04) | 0.23 | 0.86 (0.65;1.00) | 0.52 |
| Femoral (median (IQR)) | 0.89 (0.75;1.02) | 0.03 | 1.55 (1.26;2.00) | <0.0001 | 0.88 (0.79;1.02) | 0.31 | 1.50 (1.11;1.79) | 0.02 |
PXE: Pseudoxanthoma Elasticum; IQR: Interquartile Range; CS: Calcium Score; HU: Hounsfield Unit; PET-CT: Positron Emission Tomography combined with Computed Tomography; 18F; FDG: 18F-Flurodeoxyglucose; 18F-NaF: 18F-Sodium Fluorure; SUV: Standard Unit Value; TBR: Tissue-to-Blood pool Ratio.