Figure 4.

Mutation and copy number gains of genes related to the WNT signaling pathway and ERBB receptor family members in non‐ampullary duodenal lesions. Pathological types (small intestinal or gastric type) and CIMP status, mutations in WNT signaling‐associated genes, and β‐catenin expression status are shown at the top. Mutations and copy number gains in ERBB receptor family members are shown in the middle panels and lower panels. Frequencies of mutations and copy number gains in respective genes as well as β‐catenin expression positivity are shown on the right. CIMP, CpG island methylator phenotype.