Table 2.
Crude mean (SD) OAB‐specific US$ costs per patient from initiation of pharmacotherapy to end of study period, ITT cohort (n = 1662) and IPT cohort (n = 54 066; overall and among the subgroups who went on to target therapy)
| IPT Cohort | ITT Cohort | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| All | Combi mira/AM | onabotulinumtoxinA (n = 244) | SNS | PTNS | All | Combi mira/AM | onabotulinumtoxinA | SNS | PTNS | |
| (n = 54,066) | (n = 245) | (n = 188) | (n = 98) | (n = 1,662) | (n = 427) | (n = 456) | (n = 535) | (n = 245) | ||
| Medications | ||||||||||
| Mean (SD) | 1203 (1872) | 5435 (3867) | 1670 (1872) | 1364 (1738) | 1846 (1954) | 2552 (4001) | 7706 (4093) | 754 (1867) | 580 (1729) | 1223 (1965) |
| Inpatient visits (hospitalizations) | ||||||||||
| Mean (SD) | 45 (1298) | 0 (0) | 214 (2515) | 61 (812) | 0 (0) | 64 (1190) | 34 (480) | 102 (1373) | 0 (8) | 187 (2386) |
| ER visits (inpatient and outpatient) | ||||||||||
| Mean (SD) | 7 (225) | 0 (0) | 14 (142) | 10 (142) | 0 (0) | 14 (342) | 0 (0) | 5 (55) | 3 (50) | 79 (884) |
| Outpatient visits | ||||||||||
| Mean (SD) | 538 (3312) | 1597 (5086) | 8299 (12 564) | 38 528 (27 895) | 4780 (4466) | 12 702 (20 229) | 1633 (5976) | 7670 (11 065) | 29 122 (26 590) | 5549 (6625) |
| Physician visits, mean (SD) | ||||||||||
| GP | 45 (327) | 81 (233) | 502 (3315) | 637 (2597) | 173 (1030) | 337 (1789) | 75 (310) | 245 (854) | 650 (2867) | 278 (1383) |
| Specialist | 206 (688) | 646 (1619) | 2415 (2490) | 4123 (4246) | 3547 (2953) | 1998 (2788) | 580 (1474) | 2100 (2510) | 2446 (3166) | 3328 (3141) |
| Other | 287 (2962) | 870 (3743) | 5382 (11 202) | 33 768 (26 803) | 1060 (2777) | 10 367 (19 376) | 978 (5380) | 5325 (10 272) | 26 026 (25 919) | 1942 (5250) |
| Procedures | ||||||||||
| Mean (SD) | 71 (1625) | 804 (4022) | 2883 (6838) | 13 867 (20 469) | 2844 (2116) | 5719 (13 091) | 486 (3178) | 2774 (4573) | 13 250 (20 322) | 3889 (3794) |
| Total, mean (SD) | 1787 (4105) | 7032 (5854) | 10 183 (13 725) | 39 954 (28 113) | 6626 (5173) | 15 318 (19 648) | 9373 (7112) | 8527 (11 333) | 29 702 (26 802) | 6959 (7533) |
Abbreviations: AM, antimuscarinic; ER, emergency room; GP, general practitioner; IPT, incident pharmacotherapy cohort; IQR, interquartile range; mira, mirabegron; OAB, overactive bladder; PPPS, per‐member‐per‐month; PTNS, percutaneous tibial nerve stimulation; SD, standard deviation; SNS, sacral nerve stimulation.