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. 2020 Oct 29;9(11):2374. doi: 10.3390/cells9112374

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Combined single-cell analysis of BAL from severe- and mild-COVID-19 patients compared to healthy subjects. A total of 16,310 BAL-derived single cells from two healthy subjects, three patients with mild COVID-19, and five patients with severe COVID-19 were subjected to singl- cell analysis. Data are displayed as heat map (a) with the enriched cell population indicated on the left. (b) UMAP dimensionality reduction visualization of cell clusters corresponding to data presented in panel a with selected enriched cell populations indicated. MΦ: macrophages.