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. 2020 Oct 29;9(11):2374. doi: 10.3390/cells9112374

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Similarities in transcriptome data from BAL and peripheral blood mononuclear cell (PBMCs) in COVID-19 patients. (a) Hierarchical clustering summarizing differential gene expression (log2) in PBMCs from COVID-19 and normal controls, highlighting enriched functional categories (GO). (b) Venny diagram illustrating the aberrantly expressed genes in common in severe- and mild-Covid-19 BAL and PBMC, with 11 genes in common to the three categories. (c) Volcano plot depicting selected genes common to BAL and PBMCs, indicating upregulated (red) and downregulated (blue) genes.