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FBXW7 protein expression in cutaneous melanoma. Representative images of (A) strong FBXW7 immunostaining in pT1 melanoma, (B) moderate FBXW7 immunostaining in pT2 melanoma, (C) weak FBXW7 staining in pT3 melanoma and (D) negative FBXW7 staining in pT4 melanoma. Marked areas indicate FBXW7 staining in malignant melanocytes. Magnification, ×100. FBXW7, F-box and WD repeat domain-containing 7; pT, pathological tumor stage.
