Table 2.

Annual percentage changes and average annual percentage changes of average age at diagnosis from 1975 to 2016 by HNC site.

Characteristics	Oropharyngeal Cancer			Other Head and Neck Cancer
	Year Range	APC (95% CI)	Average APC from 1975 to 2016 (95% CI)	Year Range	APC (95% CI)	Average APC from 1975 to 2016 (95% CI)
Overall			0.00 (−0.09, 0.09)			0.08 (0.04, 0.12)
	1975–1996	0.00 (−0.06, 0.07)		1975–1991	0.18 (0.13, 0.22)
	1996–2002	−0.88 (−1.43, −0.32)		1991–2002	−0.09 (−0.19, 0.01)
	2002–2016	0.37 (0.28, 0.45)		2002–2016	0.10 (0.04, 0.17)
Sex
Female			0.12 (−0.01, 0.25)			0.11 (0.06, 0.15)
	1975–1992	0.40 (0.25, 0.54)		1975–1991	0.31 (0.21, 0.41)
	1992–2007	−0.31 (−0.53, −0.08)		1991–2016	−0.03 (−0.08, 0.03)
	2007–2016	0.31 (−0.07, 0.69)
Male			−0.03 (−0.15, 0.09)			0.07 (0.03, 0.10)
	1975–1997	−0.12 (−0.18, −0.06)		1975–1989	0.14 (0.09, 0.20)
	1997–2001	−1.20 (−2.36, −0.02)		1989–2002	−0.10 (−0.18, −0.02)
	2001–2016	0.42 (0.35, 0.49)		2002–2016	0.14 (0.08, 0.21)
Race/Ethnicity
Hispanic			−0.09 (−0.25, 0.07)			−0.03 (−0.10, 0.04)
	1975–2007	−0.26 (−0.42, −0.11)		1975–2016	−0.03 (−0.10, 0.04)
	2007–2016	0.53 (0.01, 1.04)
Non-Hispanic API/AIAN			−0.11 (−0.23, −0.0008)			0.14 (0.07, 0.20)
	1975–2016	−0.11 (−0.23, −0.0008)		1975–2016	0.14 (0.07, 0.20)
Non-Hispanic Black			0.14 (0.09, 0.20)			0.14 (0.11, 0.18)
	1975–2016	0.14 (0.09, 0.20)		1975–2016	0.14 (0.11, 0.18)
Non-Hispanic White			−0.01 (−0.07, 0.05)			0.10 (0.05, 0.14)
	1975–1989	0.13 (0.02, 0.24)		1975–1991	0.20 (0.15, 0.24)
	1989–2005	−0.43 (−0.53, −0.33)		1991–2010	−0.04 (−0.08, 0.01)
	2005–2016	0.43 (0.32, 0.54)		2010–2016	0.25 (0.01, 0.48)

Note: API/AIAN = Asian/Pacific Islander/American Indian/Alaska Native; APC = Annual Percentage Change; CI = Confidence Interval.