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The central carbohydrate metabolism pathways involving thiamine pyrophosphate (TPP)-dependent enzymes. TPP serves as a cofactor for steps regulating the pentose phosphate cycle, fate of pyruvate and the tricarboxylic acid cycle. TKT; transketolase, PDH; pyruvate dehydrogenase, KGDH; α-ketoglutarate dehydrogenase.
