Figure 2.
The central carbohydrate metabolism pathways involving thiamine pyrophosphate (TPP)-dependent enzymes. TPP serves as a cofactor for steps regulating the pentose phosphate cycle, fate of pyruvate and the tricarboxylic acid cycle. TKT; transketolase, PDH; pyruvate dehydrogenase, KGDH; α-ketoglutarate dehydrogenase.