Table 4.
Antimicrobial activity exerted by broth cultures (BCs) and cell-free supernatants (CFSs) of A. kunkeei K18, K34, K45 and DSM 12361 and L. rhamnosus GG ATCC 53103 (producers) against S. aureus ATCC 29213, E. faecalis ATCC 29212, E. coli ATCC 11775, E. coli ATCC 25404 and P. aeruginosa ATCC 27853 (indicators). Only zones of inhibition (ZOIs) ≥ 8.0 mm are reported.
| Indicator Strains | Zone Diameter Breakpoints (R<) * | Producer Strains (Broth Cultures, BC; Cell-Free Supernatants, CFS) | ||||||
|---|---|---|---|---|---|---|---|---|
| K18 | K34 | K45 | DSM 12361 | ATCC 53103 | MRS pH 3.4 | |||
| S. aureus ATCC 29213 | 17.0–26.0 | BC | - | - | - | - | - | - |
| CFS | - | - | - | - | - | - | ||
| E. faecalis ATCC 29212 | 8.0–22.0 | BC | - | 15.4 ± 0.2 | - | - | - | - |
| CFS | - | 14.2 ± 0.3 | - | - | - | - | ||
| E. coli ATCC 11775 | 12.0–25.0 | BC | - | - | - | - | - | - |
| CFS | - | - | - | - | - | - | ||
| E. coli ATCC 25404 | 12.0–25.0 | BC | - | - | - | - | - | - |
| CFS | - | - | - | - | - | - | ||
| P. aeruginosa ATCC 27853 | 15.0–26.0 | BC | 12.4 ± 0.2 | 14.0 ± 0.1 | 12.0 ± 0.2 | - | - | - |
| CFS | 11.0 ± 0.1 | 12.5 ± 0.2 | 11.0 ± 0.1 | - | - | - | ||
* Intervals of zone diameter breakpoints (mm) reported for resistance (R<) of the bacterial species used as indicators against different antibiotics (available at https://eucast.org/clinical_breakpoints/).