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. 2020 Oct 26;9(11):2354. doi: 10.3390/cells9112354
APAP Acetaminophen
AIHI APAP-induced hepatocellularinjury
ALF Acute liver failure
NAPQI N-acetyl-p-benzoquinone imine
GSH Reduced glutathione
JNK c-Jun N-terminal kinase
NAC N-acetyl cysteine
ROS Reactive oxygen species
TAMH Transforming growth factor-α transgenic mouse hepatocytes
CQ Chloroquine
BSA Bovine serum albumin
TMRM Tetramethylrhodamine methyl ester
FCCP Carbonyl cyanide-p-trifluoromethoxyphenylhydrazone
SDS Sodium dodecyl sulfate
TBS-T Tris-buffered saline-tween 20
GSSG Oxidised glutathione
LC3B Microtubule-associated proteins 1A/1B light chain 3B
AMPK AMP-activated protein kinase
ULK1 Unc-51-like autophagy activating kinase 1
mTORC1 Mechanistic target of rapamycin complex 1
TOM Translocases of outer membrane
PGC-1α Peroxisome proliferator-activated receptor gamma coactivator 1-alpha
TFAM Transcription of transcription factor A, mitochondrial
DILI Drug-induced liver injury
TGF-α Transforming growth factor alpha
Vps34 Phosphatidylinositol 3-kinase
NRF1 Nuclear respiratory factor 1
NRF2 Nuclear respiratory factor 2
Tim23 Presequence translocase of the inner membrane
GPx Glutathione peroxidase
MPT Membrane permeability transition
MPK-1 Mitogen-activated protein kinase phosphatase-1
GCLC Glutamate-cysteine ligase, catalytic subunit
GCLM Glutamate-cysteine ligase, modifier subunit
ND1 Mitochondrially encoded NADH dehydrogenase 1
HK2 Hexokinase 2
GAPDH Glyceraldehyde-3-phosphate dehydrogenase
VDAC1 Voltage dependent anion channel 1
p70S6K Ribosomal protein S6 kinase B1
RT-PCR Reverse transcription-polymerase chain reaction