Scheme 1.

A schematic illustration of self‐assembly and fibrillar transformation of the acid‐activated peptide‐porphyrin (PWG) nanoparticles and their application in PDT. Protonation of PWG (PWG 1) in the acidic microenvironment of tumor tissue and lysosomes induces the transformation of the nanoparticles into aggregated nanofibers, which has a beneficial effect on singlet oxygen generation.