Table 2.
Multidrug-resistant pathogenic Escherichia coli isolates (%) from weaned piglets with diarrhea in Korea from 2007 to 2017.
| Antimicrobial Subclass 1 | Before the Ban on AGPs | After the Ban on AGPs | Total (2007–2017) (n = 690) |
Differences in before and after Ban on AGPs 2 | |||||
|---|---|---|---|---|---|---|---|---|---|
| 2007–2009 (n = 118) | 2010–2011 (n = 100) | Subtotal (2007–2011) (n = 218) |
2012–2013 (n = 141) | 2014–2015 (n = 161) | 2016–2017 (n = 170) | Subtotal (2012–2017) (n = 472) |
|||
| 0 subclass ** | 4 (3.4) | 0 (0.0) | 4 (1.8) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 4 (0.6) | (1.8) |
| 1 subclass | 2 (1.7) | 0 (0.0) | 2 (0.9) | 3 (2.1) | 1 (0.6) | 2 (1.2) | 6 (1.3) | 8 (1.2) | (−0.4) |
| 2 subclasses | 0 (0.0) | 5 (5.0) | 5 (2.3) | 4 (2.8) | 4 (2.5) | 2 (1.2) | 10 (2.1) | 15 (2.2) | (0.2) |
| 3 subclasses | 1 (0.8) | 2 (2.0) | 3 (1.4) | 3 (2.1) | 10 (6.2) | 6 (3.5) | 19 (4.0) | 22 (3.2) | (−2.6) |
| 4 subclasses | 2 (1.7) | 12 (12.0) | 14 (6.4) | 7 (5.0) | 14 (8.7) | 23 (13.5) | 44 (9.3) | 58 (8.4) | (−2.9) |
| 5 subclasses | 10 (8.5) | 21 (21.0) | 31 (14.2) | 21 (14.9) | 17 (10.6) | 34 (20.0) | 72 (15.3) | 103 (14.9) | (−1.1) |
| 6 subclasses | 27 (22.9) | 13 (13.0) | 40 (18.3) | 17 (12.1) | 19 (11.8) | 34 (20.0) | 70 (14.8) | 110 (15.9) | (3.5) |
| 7 subclasses | 28 (23.7) | 22 (22.0) | 50 (22.9) | 32 (22.7) | 26 (16.1) | 41 (24.1) | 99 (21.0) | 149 (21.6) | (1.9) |
| 8 subclasses | 17 (14.4) | 6 (6.0) | 23 (10.6) | 23 (16.3) | 36 (22.4) | 17 (10.0) | 76 (16.1) | 99 (14.3) | (−5.5) |
| 9 subclasses | 11 (9.3) | 8 (8.0) | 19 (8.7) | 11 (7.8) | 19 (11.8) | 7 (4.1) | 37 (7.8) | 56 (8.1) | (7.9) |
| 10 subclasses | 16 (13.6) | 10 (10.0) | 26 (11.9) | 18 (12.8) | 13 (8.1) | 4 (2.4) | 35 (7.4) | 61 (8.8) | (4.5) |
| 11 subclasses | 0 (0.0) | 1 (1.0) | 1 (0.5) | 2 (1.4) | 2 (1.2) | 0 (0.0) | 4 (0.8) | 5 (0.7) | (−0.3) |
| Multi-resistant (≥3 Subclasses) | 112 (94.9) | 95 (95.0) | 207 (95.0) | 134 (95.0) | 156 (96.9) | 166 (97.6) | 456 (96.6) | 663 (96.1) | (−2.6) |
1 Significant differences between before (2007–2011) and after (2012–2017) the ban on antibiotic growth promoters in feed were expressed as ** (p < 0.01) Antimicrobial subclass are defined by the Clinical and Laboratory Standards Institute. 2 Difference of the subtotals before (2007–2011) minus after (2012–2017) the ban on antibiotic growth promoters in feed.