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| Factor | Does it Affect Spread? | Does it Affect Diffusion? |
|---|---|---|
| Protein Composition | No | No |
| Molecular Size | No | No |
| Neurotoxin Potency | No | No |
| Local Receptor Density | No | Yes |
| Dose | No | Yes |
| Patient Factors (age, sex, weight, etc) | Yes | No |
| Injection Technique (ie, reconstitution volume, number of injections) | Yes | No |
| Neurotoxin Concentration | Yes | No |
| Anatomic Site | Yes | Yes |
