Table 2.
Top 10 genes that were significantly increased in the lacrimal glands of male NOD mice at and after 6 weeks of age; data from RNA‐seq, showing fold change
| Gene ID | Gene symbol | Description | NOD_4wk/ BALBc_4wk | NOD_6wk/ BALBc_6wk | NOD_10wk/ BALBc_10wk | NOD_6wk/ NOD_4wk | NOD_10wk/ NOD_6wk | BALBc_6wk/ BALBc_4wk | BALBc_10wk/ BALBc_6wk |
|---|---|---|---|---|---|---|---|---|---|
| Satisfying | −2 <, < 2 | 2 <, ascending order | 2 < | 2 < | |||||
| 23833 | Cd52 | CD52 antigen | 1.13 | 16.03 | 14.94 | 14.04 | 1.26 | −1.01 | 1.35 |
| 20304 | Ccl5 | chemokine (C‐C motif) ligand 5 | 1.08 | 12.59 | 10.09 | 10.57 | −1.36 | −1.10 | −1.09 |
| 14969 | H2‐Eb1 | histocompatibility 2, class II antigen E beta | 1.30 | 11.63 | 12.12 | 13.42 | 1.18 | 1.51 | 1.13 |
| 13040 | Ctss | cathepsin S | 1.58 | 11.28 | 9.88 | 7.22 | 1.02 | 1.01 | 1.17 |
| 110454 | Ly6a | lymphocyte antigen 6 complex, locus A | 1.95 | 10.43 | 13.51 | 5.40 | −1.12 | 1.01 | −1.45 |
| 14960 | H2‐Aa | histocompatibility 2, class II antigen A, alpha | 1.14 | 9.91 | 9.72 | 11.72 | 1.19 | 1.35 | 1.21 |
| 16149 | Cd74 | CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen‐associated) | −1.00 | 9.78 | 10.60 | 12.73 | 1.31 | 1.30 | 1.21 |
| 107350 | AW112010 | expressed sequence AW112010 | 1.27 | 9.26 | 8.97 | 8.07 | −1.12 | 1.10 | −1.09 |
| 55985 | Cxcl13 | chemokine (C–X–C motif) ligand 13 | 1.52 | 9.03 | 22.31 | 6.05 | 2.55 | 1.02 | 1.03 |
| 14469 | Gbp2 | guanylate binding protein 2 | 1.23 | 8.91 | 7.57 | 6.67 | 1.03 | −1.08 | 1.21 |