4-HNE |
4-hydroxynonenal; |
AA |
arachidonic acid; |
ACSL4 |
Acyl-CoA synthetase long-chain family member 4; |
AD |
Alzheimer’s disease; |
ALS |
Amyotrophic lateral sclerosis; |
BSO |
L-buthionine-(S,R)-sulfoximine; |
CNS |
central nervous system; |
DFO |
Deferoxamine mesylate; |
DMF |
dimethyl fumarate; |
FPN |
ferroportin; |
FRDA |
Friedreich’s ataxia; |
FT |
ferritin; |
FTL |
ferritin light chain; |
FSP1 |
ferroptosis suppressor protein 1; |
FTMt |
mitochondrial ferritin; |
FXN |
frataxin; |
GPX |
glutathione peroxidase; |
GSH |
glutathione; |
HCC |
hepatocellular carcinoma cells; |
Hmox1 |
Heme Oxygenase 1; |
HSPB1 |
heat shock beta-1 protein; |
IRE |
iron response element; |
IREB2 |
RNA-binding protein 2; |
IRP |
iron-responsive element-binding protein; |
ISC |
iron-sulfur clusters; |
LIP |
labile iron pool; |
LOOH |
lipid peroxides; |
MDA |
malondialdehyde; |
NAC |
N-acetylcysteine; |
NCOA4 |
nuclear receptor coactivator 4; |
NQO1 |
quinone oxidoreductase; |
NRF2 |
Nuclear factor erythroid 2-related factor 2; |
OMOV |
Omaveloxolone; |
PE |
phosphatidylethanolamine; |
PUFAs |
Polyunsatured fatty acids; |
ROS |
reactive oxygen species; |
SeC |
Selenocysteine; |
SFN |
sulforaphane; |
Steap3 |
six-transmembrane epithelial antigen of the prostate 3; |
TF |
transferrin; |
TFR1 |
transferrin receptor complex; |
UTRs |
untranslated regions |