Table 9A.

Comparison of methylthioadenosine phosphorylase (MTAP) immunohistochemistry (IHC) and MTAP fluorescence in situ hybridization (FISH) homozygous and hemizygous deletion, and no loss (retention).

MTAP FISH scoring	MTAP IHC loss	MTAP IHC retained	Concordance between MTAP IHC and MTAP FISH hemizygous loss, homozygous loss and no loss
Homozygous Loss (n=43)	28 (includes 1 case of partial loss)	15	65% (28/43)
Hemizygous Loss (n=10)	1	9	90% (9/10)
No Loss (n=3)	0	3	100% (3/3)
Overall Concordance of MTAP IHC and MTAP FISH as a test			71% (40/56)