Table 4.

Secondary outcomes in the study groups.

Variable	HFNC group (43)	CPAP group (41)	P-value
RR, min, mean (sd)
T0	59.8 ± 7.4	57.2 ± 9.2	p = 0.151
T1	54.2 ± 7.7*	54.02 ± 6.7	p = 0.896
T24	51.9 ± 8.0*	52.2 ± 5.7*	p = 0.899
T48	51.5 ± 8.2*	51.5 ± 5.7*	p = 0.987
HR, min, mean (sd)
T0	153.6 ± 17.1	147 ± 15.5	p = 0.111
T1	148.7 ± 13.4	143.2 ± 10.0	p = 0.037
T24	144.4 ± 13.2 &	139.1 ± 11.2 &	p = 0.049
T48	138.5 ± 14.4 &	137.1 ± 10.3 &	p = 0.537
SpO2, % median (range)
T0	90 (88–91)	90 (87–91)	p = 0.856
T1	95 (94–96) #	95 (94–96) #	p = 0.462
T24	95 (94–96) #	96 (95–97) #	p = 0.144
T48	95 (94–96) #	96 (95–97) #	p = 0.105
PaO2, mmHg, mean (sd)
T0	54.3 ± 7.8	53.2 ± 9.1	p = 0.420
T24	89 (75–107) @	87 (76–112) @	p = 0.907
T48	91.5 (84.7–97.5) @	96 (81–122.25) @	p = 0.217
PaCO2, mmHg, mean (sd)
T0	42 (37–49)	42 (38–48)	p = 0.661
T24	41 (35–46)	42 (37.5–45)	p = 0.707
T48	40.5 (35–46)	41 (38–46)	p = 0.615
PH, mean (sd)
T0	7.38 ± 0.06	7.38 ± 0.07	p = 0.895
T24	7.40 (7.35–7.43)	7.37 (7.34–7.42)	p = 0.233
T48	7.38 (7.34–7.45)	7.38 (7.35–7.42)	p = 0.612

Improvement in the mean respiratory rate (RR), heart rate (HR), SpO2, PaO2, PaCO2, and PH during 48h of respiratory support. Values are expressed as mean (SD) ±SD or numbers (%).

^*RR,

^&HR,

^#SpO2,

^@PaO2, compare with T0 p < 0.05.